Introduction: Inflammation is an essential feature in the pathology of pneumonia and St eroid benefits remains unclear. Understanding role of steroids in Pneumonia and its cons equences advised Biomarker informed concordant use associated if CRP is more than 150mg/l. Method: This is a Retrospective single centre study, conduct ed from September to October 2020. All COVID patients meeting Criteria for COVID admissions were included and thos e requiring treatment with remdesivir was initiat ed as per guidelines of ICMR and the Institution protocols. Patients without CRP within 48 hours of admission were excluded. The outcome of the dis ease and other parameters were revived and recorded for analysis. Results: All registered patients were analysed and 204 patients were identified for analysis during the period evaluated for the study. Criteria for COVID admissions were based on Guidelines and severity and patients requiring treatment with Remdesivir. Many were excluded due to lack of CRP at or within 48 hours of Admission.Males; 132 and Females: 72. Males had more COVID admissions . Length of Hospitalis ation: using sk ewed dat a it is not possible to calculate Mean hence Median/Aver age is used. With Remdesivir duration of stay is av erage 12 days which is significant. Cure r ates in age subgroup population of COVID. In Younger age group and age group between 45 to 60 cure rates is better -100% and in age >75 cure rates is only 86%. Number of hypertension in covid patients is 55/204 (27%).cure rate in Hypertensive covid patients is 86% and is not significant risk factor for cure outcome. Patients with Remdesivir are at 12 times risk of getting not cured implying the group without remdesivir cure rate is better. Conclusion: CRP in ARDS/ALI(18,19)- Adults with high CRP in ARDS/ALI have favourable respons e(22) but elderly patients in ALI and High CRP have higher mortality(23) in many studies with covid(xiamin Luo). Tissue damage and MODS in COVID cause increase Inflammatory response and progression of disease(20) contributing to Mortality and Morbidity.