Worldwide, Diarrhea Is The Record Leading Cause Of Deaths In Children, With Rotavirus Being The Most Common Diarrheal Pathogen Irrespective Of The Country’s Level Of Development. It’s Recognized That Hospitalization For Rotavirus Gastroenteritis (Rv Ge) Represents The Severe End Of The Spectrum Of The Disease, For That, The Vaccine Trial Was Introduced In Our Country. Our Main Objective Was To Study The Impact Of Vaccination Program For Rotavirus (Rv) On Disease Burden Among The Lebanese Infants And Children Under 5 Years Of Age Who Have Been Diagnosed With Acute Gastroenteritis From Year 2016 To 2017. In Addition To Estimating The Effectiveness Of Both Included Vaccines In Our Country. Methods: This Was A Retrospective Database Study Between Years 2016- 2017, Wherein Data On Infants And Children Younger Than 5 Years Who Have Been Diagnosed With Acute Gastroenteritis (Ge), Has Been Collected From The Electronic Admission Database Or Other Records From The Participating Hospitals. Results: In Lebanon, The Rate Of Hospitalized Patients With Rv Ge Was Found Around 31.9 % During 2016-2017. Overall, 30.4% Were Vaccinated Against Rv Among Hospitalized Children For All Ge. Therefore, Vaccination Against Rv Was Associated With Reduction Of The Incidence Of Disease, As Well As The Clinical Severity And Number Of Hospitalizations Among Immunized Patients Compared To Those Non-Immunized. Same Effectiveness Was Found Between The 2 Types Of Vaccines. Conclusion: The Findings Of Our Study Confirm The Positive Impact Of Rv Vaccines On The Control Of Rv Diarrheal Disease In Lebanon And The Reduction Of The Disease Burden Upon Introduction Of The Rv Vaccine Into The Routine Immunization Schedule In Children. This Result Suggests That Maximizing Vaccine Coverage May Lead To Further Reductions In Ge Rv Mortality And Hospitalizations.