Background: Diarrhea is characterized by three or more loose, liquid, or watery bowel movements per day and can lead to dehydration due to fluid loss.Aim of the study: This study aimed to assess mothers’ knowledge regarding the prevention and home-based management of diarrhea in their under-five children in Tikrit City.Patients and Methods: A cross-sectional, hospital-based study was conducted on 200 mothers whose children suffered from acute diarrhea and were admitted to Salah Al-deen General Hospital in Tikrit City between June 10, 2020, and June 10, 2021. A structured questionnaire was used to assess the different treatment measures taken by mothers for their children aged 2 months to 5 years. Diarrhea was defined as acute if it lasted less than 14 days, with or without blood, fever, or vomiting. The questionnaire consisted of three sections: demographic characteristics, knowledge about diarrhea, and its management.Results: The study found no significant distribution of children by age and sex, although 58% of cases were females, and most were under 24 months of age. The majority of children came from rural areas, and over one-third of mothers were illiterate, with 25% having completed primary school. A significant association was found between type of feeding and the educational level of mothers (P<0.01). The prevalence of bloody diarrhea among the children was 11%, and 82% of the children drank tap water. Nearly half of the mothers (51%) used antibiotics to manage diarrhea, 5% used sagwa, and 15% used ORS. Mothers primarily relied on relatives or media (50%) for knowledge about using antibiotics, while 80% of those who used sagwa did so based on information from relatives. Most mothers learned about ORS from physicians and TV. A significant relationship was found between maternal education, knowledge sources, and management actions taken for diarrhea, suggesting that higher maternal education levels were associated with lower incidences of diarrhea in children.
Diarrhea is the passage of loose or watery stools occurring three or more times in a 24-hour period which means an increased frequency or decreased consistency of bowel movements, and it affects people of all ages. It is usually a symptom of an infection in the intestinal tract, which can be caused by a variety of bacterial, viral, and parasitic organisms [1-5]. Diarrhea is the second leading cause of child morbidity and mortality, especially in the developing countries. Globally, it is estimated that there are 2.5 billion episodes and 1.5 million deaths annually in children under five years [6-8]. Various preventive techniques were reported in the literatures including hygiene, diet, medications, and supplements; although according to a general classification, health care, breastfeeding, immunization, supplemental zinc, and probiotics could be used. Simple remedies could be taken to reduce the number of mortality [9-13]. Fluid therapy with Oral Rehydration Solution (ORS) and other standard home solutions, non-stop feeding during diarrhea, and continued breastfeeding are the typical treatments [14-21]. Since 1970s, ORS has been the cornerstone of management in order to prevent life-threatening dehydration associated with diarrhea. Nevertheless, only less than 40% of children with diarrhea in developing countries received the recommended treatment and there has been a little progress toward the trend in the last decades [22-26]. Diarrhea turns mortal for majority with fluid loss and accompanying severe dehydration. Timely treatment from ORS has reduced morbidity and mortality from diarrhea[27-29]. Numerous studies about the maternal awareness of proper diet of children with diarrhea suggested that knowledge of the etiologic factors, symptoms, treatment, and caring methods in diarrheal children among mothers is inadequate, [30-34]. Most of the diarrhea episodes are treated in homes, and mothers are the key caregivers in children under five years old. They are the ones who decide about the nutrition and management of diarrhea in children therefore their knowledge about this common disorder is critically important [35-37]. Early and correct identification of diseases and prompt initiation of management plays a key role in reducing diarrhea related mortality [38-40]. An important aspect of diarrhea management is replenishing fluid and electrolyte loss. Patients should be encouraged to drink diluted fruit juice, Pedialyte or Gatorade. In more severe cases of diarrhea, IV fluid rehydration may become necessary [41-44]. Eating foods that are lower in fiber may aid in making stool firmer. A bland bananas, rice, applesauce, and toast 'BRAT' diet including bananas, toast, oatmeal, white rice, applesauce and soup/broth is well tolerated and may improve symptoms [45-49]. Anti-diarrheal therapy with anti-secretory or anti-motility agents may be started to reduce the frequency of stools. However, they should be avoided in adults with bloody diarrhea or high fever because they can worsen severe intestinal infections. Empiric antibiotic therapy with an oral fluoroquinolone can be considered in patients with more severe symptoms. Probiotic supplementation has been shown to reduce the severity and duration of symptoms and should be encouraged in patients with acute diarrhea[40,41]. The treatment of chronic diarrhea is specific to the etiology. The first step is to categorize diarrhea into watery, fatty or inflammatory. Once categorized, an algorithm can be used to determine the next step in management. Most cases require additional fecal studies, lab work or imaging. More invasive procedures like colonoscopy or upper endoscopy may be required [33,42]. Variety of preventive interventions mentioned in the literature for diarrhea include drinking clean and refined water, employing modernized sanitary systems and washing the hands frequently with a soap or other disinfectants, which can decrease the risk of infection [43]. Simple remedies such as fluid therapy with Oral Rehydration Solution (ORS) and other standard homemade solutions, female education, incessant feeding at the time of diarrhea and continued breastfeeding are the common treatments, which can reduce the mortality rate [44]. However, in developing countries, the suggested remedies have been prescribed for children with diarrhea in roughly 40% of the cases and the movement towards the extensive use of these methods has been so slow over the last 10 years [35]. Although the standard of living is promoted, public hygiene has improved, water purification has become widespread and food safety is universally recognized, diarrheal disease still inflicts a considerable loss on the economy and the society [45]. Many studies on diarrhea in children have shown that proper and prompt care is essential to reduce the negative consequences. Immediate simple interventions by mothers/caregivers for childhood diarrhea is the key to save the children’s lives [46,47]. Effective interventions can prevent most diarrhea-related casualties in children<5 years old. The global coverage for most of these interventions is <50% [48]. Effective care is often insufficiently available, especially in the first 24 hours after the onset of illness and in areas where child mortality is high. Sometimes, the diarrhea can be resolved by dietary promotion and/or simultaneous adoption of typical methods used for the management of diarrhea. There has been a huge controversy about the best approach to dietary treatment of childhood diarrhea [49]. The mothers’ or caregivers’ knowledge and understanding of the types of food used in case of diarrhea may be effective in management of the disease. Promoting the habits regarding food and personal hygiene is certainly a practical method to reduce the difficulty of illness in children with diarrhea [50]. Nutrition should serve as a key for developmental intervention, as child mortality is a serious predictor of future outcomes. In fact, people who experience high levels of complications in childhood have been shown to have reduced cognition, height and maturity, and to be at risk for further complications and mortality [13]. Poor maternal perception about diarrhea and delayed care can lead to morbidity and [44]. A large number of studies conducted on mothers’ knowledge of appropriate diet for childhood diarrhea indicate that mothers have no sufficient information on the etiologic factors, symptoms, treatments and caring methods of this disease [51-53]. The aim of this study was to assess the different treatment measures taken by mothers at home to their children under-five years who suffered from diarrhea
A cross-sectional hospital based study were done on 200 mother whose babies have acute diarrhea and admitted to pediatric ward at Salah Al-Deen general hospital in Tikrit city, during the period from 10th of June 2020 to 10th June 2021 aged below 5 years.
Study acceptance from mothers were taken and acceptance from Salah Al –deen hospital. Each case (mother whose babies have acute diarrhea) were assessed by a prepared questionnaire that include (name, age, sex, residence,……etc). Diarrhea considered as acute if it was lasting less that 14 days, whether with blood or without, with fever and vomiting or without. The questionnaire was completed by an interview. It had three parts. In the first section, the demographic characteristics, including age, sex and residence. The second part, including education of mothers and the number of children were recorded. In the third part, the knowledge about diarrhea and its management were evaluated using multiple choice questions and the occupation and the number of children were recorded. In the knowledge about diarrhea and its management were evaluated using multiple-choice questions. Mothers’ knowledge regarding home treatment of acute diarrhea were taken. Some questions were, e.g: “How do you perform the breast feeding during diarrhea?” “What is ORS?” The results were putted in tables and figures for further statistical analysis
Statistical analysis
The relations between the knowledge and the variables such as age, sex, maternal education, number of children, residence and the number of children were analyzed using computerized statistically, Minitab version 17 statistic program. Comparison was carried out using Chi-square (X2) and P. value ≤ 0.5 Significant
The study showed no significant distribution of studied children to according to age and sex, although most cases were below 24 months and 58% of total cases were females, Table 4.1
Table 1: Distribution of studied children according to age and gender
Age groups (months) | Gender | |||||
Males | Females | Total | ||||
No. | % | No. | % | No. | % | |
0-12 | 22 | 44 | 28 | 56 | 50 | 25 |
13-24 | 31 | 44.29 | 39 | 55.71 | 70 | 35 |
25-36 | 14 | 42.42 | 19 | 57.58 | 33 | 17 |
37-48 | 9 | 36 | 16 | 64 | 25 | 13 |
49-60 | 8 | 36.36 | 14 | 63.64 | 22 | 11 |
Total | 84 | 42 | 116 | 58 | 200 | 100 |
X2 : 0.89 P. value: 0.92 (Non-significant)
The study showed 58% of studied children were from rural families and 42% were from urban families, Figure 1
Figure 1: Residence distribution of studied children
The study also showed that, more than one third of mothers were illiterate and 25% complete primary school, and most of illiterate and primary school mothers were from rural areas.
Table 2: Relation of educational level of mother with their residence
Educational level of mothers | Residence | |||||
Rural | Urban | Total | ||||
No. | % | No. | % | No. | % | |
Illiterate | 58 | 89.23 | 7 | 10.77 | 65 | 33 |
Primary | 32 | 65.31 | 17 | 34.69 | 49 | 25 |
Secondary | 17 | 38.64 | 27 | 61.36 | 44 | 22 |
College | 9 | 27.27 | 24 | 72.73 | 33 | 17 |
Higher Education | 0 | 0 | 9 | 100 | 9 | 5 |
Total | 116 | 58 | 84 | 42 | 200 | 100 |
X2: 47.8 P. value: 0.0001 (Highly significant)
The study revealed that 24.5% of women feed their children by breast feeding 20.5% bottle feeding, 15% mixed feeding while 40% with solid feeding, Figure 2
Figure 2: Distribution of studied mothers according to type feeding
The study revealed a significant relation between type of feeding and educational level of studied mothers (P<0.01), Table 3
Table 3: Type of feeding in regard to educational level of studied mothers
Educational level | Breast feeding | Bottle feeding | Mixed
| Solid feeding | Total
| |||||
No. | % | No. | % | No. | % | No. | % | No. | % | |
Illiterate | 24 | 36.92 | 9 | 13.85 | 7 | 10.77 | 25 | 38.46 | 65 | 33 |
Primary | 17 | 34.69 | 6 | 12 | 6 | 12.24 | 20 | 40.82 | 49 | 25 |
Secondary | 5 | 11.36 | 10 | 22.73 | 10 | 22.73 | 19 | 43.18 | 44 | 22 |
College | 3 | 9.09 | 10 | 30.30 | 6 | 18.18 | 14 | 42.42 | 33 | 17 |
Higher Education | 0 | 0 | 6 | 67 | 1 | 11 | 2 | 22 | 9 | 5 |
Total | 49 | 24.5 | 41 | 20.5 | 30 | 15 | 80 | 40 | 200 | 100 |
P. value: 0.0011
The study the prevalence of bloody diarrhea among total children enrolled in the study was 11%, Figure 3
Figure 3: Distribution of studied children according to type diarrhea
In this study, majority of diarrheal children drinking from tap water (82%), 79% were with poor sterilization conditions in their families, and some of cases were different risk factors, Table 4
Table 4: Risk factors of diarrhea
Risk Factors of diarrhea | No | % |
Poor sterilization | 157 | 79 |
No boiled water | 74 | 37 |
No. of bottles compatible with feeding | 48 | 24 |
Use tap water | 163 | 82 |
Use tanker water | 32 | 16 |
Use river water | 73 | 37 |
Others source of water | 19 | 10 |
Contact with infected cases | 22 | 11 |
P. value: 0.001
In this study, nearly half of women who children suffered from diarrhea used antibiotics (51%), while 5% uses sagwa to manage diarrhea, 15% uses ORS and only 8% use zinc or probiotic to manage diarrhea in their children, Table 5
Table 5: Action taken by mother to manage diarrhea
Action taken by mother | No | % |
Antibiotics | 102 | 51 |
Zinc | 16 | 8 |
Probiotics | 16 | 8 |
Herbal | 8 | 4 |
ORS | 30 | 15 |
Sagwa | 10 | 5 |
Milk dilution | 8 | 4 |
Change type of milk | 10 | 5 |
The study showed significant relation between relation of source of knowledge of mothers and action to manage diarrhea, in this regard, nearly half of women took their information from relative or media to use antibiotics in treatment of diarrhea, and 80% used sagwa as treatment as they know from relatives and most of them new that ORS used in management of diarrhea from physician and TV, Table 4.6.
Table 4.6: Relation of source of knowledge of mothers and action to manage diarrhea
Source of Knowledge | Antibiotics (%) | Zinc (%) | Probiotics (%) | Herbal (%) | ORS (%) | Sagwa (%) | Milk Dilution (%) | Change Type of Milk (%) |
Media | 25.49 | 37.50 | 10.34 | 25.00 | 2.04 | 10.00 | 12.50 | 20.00 |
Relatives | 25.49 | 2.00 | 3.45 | 25.00 | 2.04 | 80.00 | 0.00 | 20.00 |
Physician | 19.61 | 11.94 | 34.48 | 0.00 | 34.69 | 0.00 | 8.96 | 60.00 |
TV | 9.80 | 4.55 | 3.45 | 0.00 | 20.41 | 0.00 | 0.00 | 0.00 |
Friends | 17.65 | 0.00 | 0.00 | 37.50 | 2.04 | 10.00 | 4.17 | 0.00 |
Others | 1.96 | 0.00 | 3.45 | 12.50 | 0.00 | 0.00 | 0.00 | 0.00 |
P. value: 0.0001
The study showed significant relation between risk factors of diarrhea and educational levels of mothers and most mothers with illiterate and primary school levels have high risk of diarrhea and, Table 7
Table 7: Relation of educational level of mother with risk factor of diarrhea
Educational level | Poor sterilization | No boiled water | No. of bottles compatible with feeding | Use tap water | Use tanker water | Use river water | ||||||
No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
Illiterate | 55 | 35.03 | 23 | 31.08 | 14 | 29.17 | 56 | 34.36 | 17 | 53.13 | 40 | 54.79 |
Primary | 41 | 26.11 | 16 | 21.62 | 12 | 25.00 | 37 | 22.70 | 12 | 37.50 | 19 | 26.03 |
Secondary | 32 | 20.38 | 15 | 20.27 | 10 | 20.83 | 36 | 22.09 | 3 | 9.38 | 10 | 13.70 |
College | 22 | 14.01 | 12 | 16.22 | 6 | 12.50 | 27 | 16.56 | 0 | 0 | 4 | 5.48 |
Higher Education | 7 | 4.46 | 8 | 10.81 | 6 | 12.50 | 7 | 4.29 | 0 | 0 | 0 | 0 |
Total | 157 | 100 | 74 | 100 | 48 | 100 | 163 | 100 | 32 | 100 | 73 | 100 |
P. value: 0.0028
The study a significant relation between educational level of mother and source of knowledge about management of diarrhea, Table 8
Table 8: Relation between educational level of mother and source of knowledge about management of diarrhea
Source of knowledge | Illiterate | Primary | Secondary | College | Higher Education | Total | ||||||
No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
Media | 2 | 3.08 | 10 | 20.41 | 16 | 36.36 | 12 | 36.36 | 2 | 22.22 | 42 | 21 |
Relatives | 21 | 32.31 | 10 | 20.41 | 7 | 15.91 | 2 | 6.06 | 1 | 11.11 | 41 | 21 |
Physician | 11 | 16.92 | 17 | 34.69 | 15 | 34.09 | 19 | 57.58 | 5 | 55.56 | 67 | 34 |
Tv | 10 | 15.38 | 9 | 18.37 | 3 | 6.82 | 0 | 0 | 0 | 0 | 22 | 11 |
Friends | 19 | 29.23 | 2 | 4.08 | 2 | 4.55 | 0 | 0 | 1 | 11.11 | 24 | 12 |
Others | 2 | 3.08 | 1 | 2.04 | 1 | 2.27 | 0 | 0 | 0 | 0 | 4 | 2 |
Total | 65 | 32.5 | 49 | 24.5 | 44 | 22 | 33 | 16.5 | 9 | 4.5 | 200 | 100 |
P. value: 0.0001
The study a significant relation between educational level of mother and action taken by mother to manage diarrhea , Table 9
Table 49: Relation between educational level of mother and Action taken by mother to manage diarrhea
Action taken by mother | Illiterate | Primary | Secondary | College | Higher Education | Total | |||||
No. | % | No. | % | No. | % | No. | % | No. | % | No. | |
Antibiotics | 47 | 72.31 | 23 | 46.94 | 19 | 43.18 | 10 | 30.30 | 3 | 33.33 | 102 |
Zinc | 2 | 3.08 | 2 | 4.08 | 5 | 11.36 | 7 | 21.21 | 0 | 0 | 16 |
Probiotics | 0 | 0 | 4 | 8.16 | 6 | 13.64 | 5 | 15.15 | 1 | 11.11 | 16 |
Herbal | 0 | 0 | 0 | 0 | 4 | 9.09 | 4 | 12 | 0 | 0 | 8 |
ORS | 9 | 13.85 | 8 | 16.33 | 6 | 13.64 | 6 | 18 | 1 | 11.11 | 30 |
Sagwa | 4 | 6.15 | 5 | 10.20 | 1 | 2.27 | 0 | 0 | 0 | 0 | 10 |
Milk dilution | 0 | 0 | 3 | 6.12 | 2 | 6.82 | 2 | 6.06 | 1 | 11.11 | 10 |
Change type of milk | 3 | 4.62 | 3 | 6.12 | 1 | 2.27 | 2 | 6.06 | 2 | 22.22 | 11 |
P. value: 0.0001
The study showed no significant distribution of studied children in according to age and sex, although most cases were below 24 months and 58% of total cases were females, In agreement with our finding, [55] indicated that most diarrheal children was occurred within the age group 25-36 month followed by (25%) in the age group 13-24 month. It has been suggested that in developing countries the infection is usually acquired before five years of age [50]. The results of the present study indicated that the highest incidence of diarrhea was observed in children aged 6-24 months, which is consistent with the results of other studies [43,44]. A multiple indicators survey performed by National Centre for health information and UNICEF (2000) reported that the prevalence rate of diarrhea in children was 39.2% in children <two years old [45]. One of the reasons why the prevalence of diarrhea increases between the ages of 6 and 24 months can be the introduction of complementary food and the unsanitary preparation of weaning food [46]. As age increase, exposure to various infection sources increases hence the ultimate rate of infection [54]. The study showed 58% of studied children were from families lived in rural areas and 42% belonged to urban areas, this agree with recent studies done [56]. Furthermore, it was indicated that children living in rural areas were more vulnerable to diarrhea than their urban counterparts and children from rural households were 1.9 times more likely to have diarrhea as compared to their counterparts [34,44]. Due to poor sanitation, contact with contaminated water supply, low level of education and malnutrition. Our results support the findings of prior studies that have also described that of diarrheal children belonged to families who lived in rural areas [57,58]. People living in urban areas are provided with better access to health services, education and other social support systems which are either not available or not easily accessible to residents in rural areas [59]. The study also showed that, more than third mothers were illiterate and 25% complete primary school, and most of illiterate and primary school mothers were from rural areas. This is goes with many studies done around the world. The reason why most of the cases have illiterate mothers is that due to the usual correlation between maternal educational level and malnutrition due to much reason like the way of preparation of milk or food or the way of sterilization [60-62]. Another finding of the present study was that compared to those mothers with lower levels of education, the ones who had higher levels of education pursued a higher level of care for their children. These mothers are usually able to employ health-related information and services in a better way and are efficiently prepared to make proper decisions in this regard. This finding is coherent with the findings of the study of [63]. The study revealed that 24.5% of women feed their children by breast feeding 20.5% bottle feeding, 15% mixed feeding while 40% with solid feeding, Figure 4.2. In this study, 20.5% bottle feeding, 15% mixed feeding, and the risk of developing acute diarrhea among such infants was higher and statistically significant compared to their counter parts ( 24.5% breast feeding). This finding is consistent with the one reported from [64] who found that 40% of the cases were not exclusively breastfeed and the risk of developing acute diarrhea among such infants. [65] also found similar results. Exclusive breastfeeding limits exposure to ingestion of enteric bacteria from contaminated water, food and bottle-feeding, and offers extra protection against illness, hence reduces the episodes of diarrhea. Susceptibility to bloody diarrhea may be explained by many factors such as declining level of maternal immunity, introduction of bottle feeding and solid food which may be contaminated by enteropathogens, together with introduction of foreign material to the mouth of these children as they have learned to crawl up and pick subjects in their hands by this age, which increases the risk of exposure to fecal pathogens [19].The study revealed a significant relation between type of feeding and educational level of studied mothers (P<0.01), Table 4.2. [66] in a cross sectional study on the incidence and risk factors of diarrheal illness among children under-five years showed that relation between type of feeding and educational level of studied mothers and most of employed women practice artificial feeding. Mother’s literacy influences hygiene practices, child feeding, and sanitation practices, which in turn very important factor for childhood diarrhea [62].The study the prevalence of bloody diarrhea among total children enrolled in the study was 11%, Figure 4.3. In agreement with our finding, [55] indicated that the 13% of children suffered from diarrhea were with bloody diarrhea [67] in study done recently showed that the prevalence of bloody diarrhea among children under-five years was 10.5%. Lastly, lack of maternal hand washing was significantly associated with childhood diarrhea. The rationale for hand washing after going to latrine to reduce the load of microorganisms has been well documented as fecal-oral microorganism transmissions due to post-defecation contamination of hands and fingers is well known [68]. Several studied showed that, children whose families used home based water treatment were less likely to experience diarrhea compared to their counterparts [67-69]. This is related to water contamination during fetching, transportation and storage, which might increase the risk of diarrhea [19]. Our finding was consistent with the results of the study conducted [70] who acute infective bloody diarrhea in children below five years admitted to children welfare hospital in Medical City-Baghdad who showed a significant association with diarrhea morbidity. This difference might be attributed to less information exposure about the risk the factors of acute diarrhea and their prevention methods among the participants of this study [20]. Consistent with our findings, several recent global and local studies recognized that access to an improved water source for drinking purpose reduces the morbidity related to diarrheal diseases [71-73]. In another study, diarrhea wass strongly associated with the source of drinking water, as it is more prevalent among citizens who are relying on non-improved water sources than those using improved water sources for drinking [74]. In contrast to our findings, a case–control study among hospitalized children in the Gaza Strip indicated that no relationship exists between the source of drinking water and the incidence of diarrhea [75]. This incompatible result may be either due to the heterogeneity of the study sample, Nonetheless, there is a growing body of evidence suggesting that improved sources of water are not utterly safe [76].In this study, nearly half of women who children suffered from diarrhea used antibiotics (51%), while 5% uses sagwa to manage diarrhea, 15% uses ORS and only 8% use zinc or probiotic to manage diarrhea in their children, The main problem with acute diarrhea is its ability to cause rapid fluid loss through stools in addition to electrolytes loss. Different epidemiological studied indicated that most of the episodes of diarrhea are treated in homes, and mothers are key care-givers in diarrhea and the poor knowledge of the mothers requires to be addressed by the health system[77-79]. In similar study, [80] indicated that half of mother did not know any type of fluids used for management of diarrhea at home and 18.1% knew that ORS is one of the fluids used in diarrhea. In study done [81] showed that the management options used by mothers to manage their children during diarrhea were giving antimicrobials drugs (38.3%), treatment at health facilities (24.9%), herbal medication (19.3%), homemade fluids (15%) and ORS (12.5%) respectively. Similar study in Nigeria [82] revealed that mothers used treatment at health facility (32.9%), ORS (54.8%) and homemade fluids (6.0%) respectively as an important measure to control diarrhea. In addition, treatment at health facilities (45.3%), herbal medication (7.7%) and homemade fluids (13.4%) were the management options used by mothers as reported by the study conducted in Kenya [83]. Integrated Community case Management of Childhood Illness (ICCM) strategy recommends that uncomplicated diarrhea could be managed successfully at home by continuing to feed the child, offering more fluids and administering Oral Rehydration Solution (ORS) correctly. Many factors affecting the morbidity and mortality of the diarrhea like antibiotics abuse, but the herbal (sagwa) use appears to be one of significant factor in our community [84]. The use of herbal products and supplements has increased over the last three decades with at least 80% of people worldwide depend on them. Many of these herbs are still unlicensed as well as their use is not monitored [85,86]. Sagwa use is a common problem in our community especially in rural areas where most of admitted patients were from the rural area since mothers from these areas are more likely to use the sagwa due to the low level of their education, low socioeconomic status of the families and easy accessibility to sagwa. moreover, thinking of the sagwa is safer than the medications as well as difficulty access the health centers [87,88]. The health education plays major role in preventing the use of sagwa in these children. Sagwa intake was more common in children of low education level or illiterate mothers and primary school mother, similar results was concluded in a study done in Iraq [86]. Since illiterate mother has no proper ideas about treating diarrheal disease and easily misled by others to use sagwa, and she cannot appreciate the biohazards of sagwa to their children [88]. Multiple studies reported mothers beliefs that modern medicines are powerful , and more effective in treating diarrhea than ORS [45,50]. Multiple studies reported drugs were widely available and affordable in the public and private sector, typically without prescription [69,71]. In many contexts, mothers stocked drugs at home, purchasing them in advance or saving leftover medication from previous illnesses [19,66,67].The study showed significant relation between relation of source of knowledge of mothers and action to manage diarrhea, in this regard, nearly half of women took their information from relative or media to use antibiotics in treatment of diarrhea, and 80% used sagwa as treatment as they know from relatives and most of them new that ORS used in management of diarrhea from physician and TV. In similar studies, mothers with good knowledge about control of diarrhea had have better results due to the source of information for good management [87,88]. Similar finding was observed from studies conducted in different countries in which better educated mothers had good knowledge [91,92]. In another study, the knowledge of ORS packets was lowest among mothers who were not regularly exposed to any mass media [93]. Another study revealed that caregivers’ previous experience and seeking advice from health facilities were found to be the positive determinants of ORT intake [94]. In another study the mothers who received their information from media and personal reading had better knowledge compared to those whom their source of the information was their physician or their relatives. Studies showed that the former experiences of the mothers are related to their knowledge about the management of diarrhea [95]. The study showed that and most children belonged mothers with illiterate and primary school levels have most risk factors of diarrhea and there was significant relation between risk factors of diarrhea and educational levels of mothers, Table 4.7. [77] study identified that mothers who have primary education and secondary and above education were 5 and 11 times more likely to have good knowledge about risk factors of diarrhea as compared to illiterates. Similarly, educational status of mother was significantly associated in studies conducted in India, Iran, and Nigeria [96-98]. The study a revealed significant relation between educational level of mother and source of knowledge about management of diarrhea, Table 4.8. The fact is that as the educational level of caregivers increased, the level of awareness and knowledge increases. This is the general truth that mothers who get information from television, radio newspaper, friends, and so forth about diarrhea know more about home management of diarrhea. Similarly, the source of information was also significantly associated with knowledge in the study conducted in Iran [99]. Other studies has also identified that mothers who had no information about diarrhea were by less likely to have the good practice compared with their counterparts. This may be due to the fact that mothers who had information about diarrhea have a good opportunity to manage diarrhea at home [100,101]. The study showed a significant relation between educational level of mother and action taken by mother to manage diarrhea , The study that 50.33% of women use ORS to treat diarrhea was with primary educational level, 16.67% for each of illiterate and secondary level. [77] study identified that mothers who were illiterate and educated till primary school were by 94.8% and 85.7% less likely to practice more as compared to those mothers who had secondary and above educational level. This also supported by the studies conducted at different part in the worlds [96-98]. The justification is that as the educational level of mothers increased, they become more skillful towards diarrhea management. Mothers' basic knowledge about diarrhoea depends on various factors such as educational status, prior experience of managing the disease and even ethnicity [102-104]. Studies in the literature show that though most of the mothers were familiar with the term oral rehydration solution (ORS), there were knowledge gaps as regards its correct preparation and administration [105,106]. The signs of dehydration due to diarrhoea remain unnoticed by the majority of the mothers. [107,108]. There are certain fluids which are beneficial to give during diarrhoea but most mothers in a rural community in Kenya were unaware of most of these
The authors declare that they have no conflict of interest
No funding sources
The study was approved by the College of Medicine, Tikrit, University.
Kliegman RM, Lye PS, Bordini BJ, Toth H, Basel D. Nelson Pediatric Symptom-Based Diagnosis E-Book. Elsevier Health Sciences; 2017 Mar 8.
Horn LM, Hajat A, Sheppard L, Quinn C, Colborn J, Zermoglio MF, Gudo ES, Marrufo T, Ebi KL. Association between precipitation and diarrheal disease in Mozambique. International journal of environmental research and public health. 2018 Apr;15(4):709.
D Levine GA, Walson JL, Atlas HE, Lamberti LM, Pavlinac PB. Defining pediatric diarrhea in low-resource settings. Journal of the Pediatric Infectious Diseases Society. 2017 Sep 1;6(3):289-93.
Duong VT, Tuyen HT, Van Minh P, Campbell JI, Phuc HL, Nhu TD, Tu LT, Chau TT, Nhi LT, Hung NT, Ngoc NM. No clinical benefit of empirical antimicrobial therapy for pediatric diarrhea in a high-usage, high-resistance setting. Clinical Infectious Diseases. 2018 Feb 1;66(4):504-11.
Wu W, Shen N, Luo L, Deng Z, Chen J, Tao Y, Mo X, Cao Q. Fecal microbiota transplantation before hematopoietic stem cell transplantation in a pediatric case of chronic diarrhea with a FOXP3 mutation. Pediatrics & Neonatology. 2021 Mar 1;62(2):172-80.
Guarino A, Vecchio AL, Dias JA, Berkley JA, Boey C, Bruzzese D, Cohen MB, Cruchet S, Liguoro I, Salazar-Lindo E, Sandhu B. Universal recommendations for the management of acute diarrhea in nonmalnourished children. Journal of pediatric gastroenterology and nutrition. 2018 Nov 1;67(5):586.
Zhou Y, Zhu X, Hou H, Lu Y, Yu J, Mao L, Mao L, Sun Z. Characteristics of diarrheagenic Escherichia coli among children under 5 years of age with acute diarrhea: a hospital based study. BMC infectious diseases. 2018 Dec;18(1):1-0.
Florez ID, Veroniki AA, Al Khalifah R, Yepes-Nuñez JJ, Sierra JM, Vernooij RW, Acosta-Reyes J, Granados CM, Pérez-Gaxiola G, Cuello-Garcia C, Zea AM. Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: a systematic review and network meta-analysis. PLoS One. 2018 Dec 5;13(12):e0207701.
Adane M, Mengistie B, Medhin G, Kloos H, Mulat W. Piped water supply interruptions and acute diarrhea among under-five children in Addis Ababa slums, Ethiopia: A matched case-control study. PloS one. 2017 Jul 19;12(7):e0181516.
Anteneh ZA, Andargie K, Tarekegn M. Prevalence and determinants of acute diarrhea among children younger than five years old in Jabithennan District, Northwest Ethiopia, 2014. BMC public health. 2017 Dec;17(1):1-8.
Cox FE. Concomitant infections, parasites and immune responses. Parasitology. 2001 Mar;122(S1):S23-38.
Harb A, Abraham S, Rusdi B, Laird T, O’Dea M, Habib I. Molecular detection and epidemiological features of selected bacterial, viral, and parasitic enteropathogens in stool specimens from children with acute diarrhea in Thi-Qar Governorate, Iraq. International journal of environmental research and public health. 2019 Jan;16(9):1573.
Lu T, Yin L, Chen R, Zhang H, Cai J, Li M, Dai L, Zhu C, Zhang Y, Xiang F, Wang L. Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial. Health and quality of life outcomes. 2021 Dec;19(1):1-1.
Zhou SX, Wang LP, Liu MY, Zhang HY, Lu QB, Shi LS, Ren X, Wang YF, Lin SH, Zhang CH, Geng MJ. Characteristics of diarrheagenic Escherichia coli among patients with acute diarrhea in China, 2009‒2018. Journal of Infection. 2021 Aug 3.
Anteneh ZA, Andargie K, Tarekegn M. Prevalence and determinants of acute diarrhea among children younger than five years old in Jabithennan District, Northwest Ethiopia, 2014. BMC public health. 2017 Dec;17(1):1-8.
Abuzerr S, Nasseri S, Yunesian M, Hadi M, Zinszer K, Mahvi AH, Nabizadeh R, Abu Mustafa A, Mohammed SH. Water, sanitation, and hygiene risk factors of acute diarrhea among children under five years in the Gaza Strip. Journal of Water, Sanitation and Hygiene for Development. 2020 Mar 1;10(1):111-23.
Adane M, Mengistie B, Mulat W, Medhin G, Kloos H. The most important recommended times of hand washing with soap and water in preventing the occurrence of acute diarrhea among children under five years of age in slums of Addis Ababa, Ethiopia. Journal of community health. 2018 Apr;43(2):400-5.
Hines RL, Marschall K. Stoelting's anesthesia and co-existing Disease. Elsevier Health Sciences; 2008 Jun 5.
Getachew B, Mengistie B, Mesfin F, Argaw R. Factors associated with acute diarrhea among children aged 0-59 months in Harar town, eastern Ethiopia. East African Journal of Health and Biomedical Sciences. 2018 Nov 8;2(1):26-35.
Guarino A, Vecchio AL, Dias JA, Berkley JA, Boey C, Bruzzese D, Cohen MB, Cruchet S, Liguoro I, Salazar-Lindo E, Sandhu B. Universal recommendations for the management of acute diarrhea in nonmalnourished children. Journal of pediatric gastroenterology and nutrition. 2018 Nov 1;67(5):586.
Zhou Y, Zhu X, Hou H, Lu Y, Yu J, Mao L, Mao L, Sun Z. Characteristics of diarrheagenic Escherichia coli among children under 5 years of age with acute diarrhea: a hospital based study. BMC infectious diseases. 2018 Dec;18(1):1-0.
Florez ID, Veroniki AA, Al Khalifah R, Yepes-Nuñez JJ, Sierra JM, Vernooij RW, Acosta-Reyes J, Granados CM, Pérez-Gaxiola G, Cuello-Garcia C, Zea AM. Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: a systematic review and network meta-analysis. PLoS One. 2018 Dec 5;13(12):e0207701.
Yang B, Lu P, Li MX, Cai XL, Xiong WY, Hou HJ, Ha XQ. A meta-analysis of the effects of probiotics and synbiotics in children with acute diarrhea. Medicine. 2019 Sep;98(37)..
Li YT, Xu H, Ye JZ, Wu WR, Shi D, Fang DQ, Liu Y, Li LJ. Efficacy of Lactobacillus rhamnosus GG in treatment of acute pediatric diarrhea: A systematic review with meta-analysis. World journal of gastroenterology. 2019 Sep 7;25(33):4999.
Shrivastava AK, Kumar S, Mohakud NK, Suar M, Sahu PS. Multiple etiologies of infectious diarrhea and concurrent infections in a pediatric outpatient-based screening study in Odisha, India. Gut pathogens. 2017 Dec;9(1):1-2.
Tian Y, Chughtai AA, Gao Z, Yan H, Chen Y, Liu B, Huo D, Jia L, Wang Q, MacIntyre CR. Prevalence and genotypes of group A rotavirus among outpatient children under five years old with diarrhea in Beijing, China, 2011–2016. BMC infectious diseases. 2018 Dec;18(1):1-1.
Wasihun AG, Dejene TA, Teferi M, Marugán J, Negash L, Yemane D, McGuigan KG. Risk factors for diarrhoea and malnutrition among children under the age of 5 years in the Tigray Region of Northern Ethiopia. PLoS One. 2018 Nov 26;13(11):e0207743..
Burnett E, Parashar UD, Tate JE. Global impact of rotavirus vaccination on diarrhea hospitalizations and deaths among children< 5 years old: 2006–2019. The Journal of infectious diseases. 2020 Nov 15;222(10):1731-9.
Reiner Jr RC, Graetz N, Casey DC, Troeger C, Garcia GM, Mosser JF, Deshpande A, Swartz SJ, Ray SE, Blacker BF, Rao PC. Variation in childhood diarrheal morbidity and mortality in Africa, 2000–2015. New England Journal of Medicine. 2018 Sep 20;379(12):1128-38.
Boadi KO, Kuitunen M. Childhood diarrheal morbidity in the Accra Metropolitan Area, Ghana: socio-economic, environmental and behavioral risk determinants. Journal of Health & Population in Developing Countries. 2005 Mar 15;7(1):15-22.
Bitew BD, Woldu W, Gizaw Z. Childhood diarrheal morbidity and sanitation predictors in a nomadic community. Italian journal of pediatrics. 2017 Dec;43(1):1-8.
Solomon ET, Gari SR, Kloos H, Mengistie B. Diarrheal morbidity and predisposing factors among children under 5 years of age in rural East Ethiopia. Tropical Medicine and Health. 2020 Dec;48(1):1-0.
Solomon ET, Gari SR, Kloos H, Mengistie B. Diarrheal morbidity and predisposing factors among children under 5 years of age in rural East Ethiopia. Tropical Medicine and Health. 2020 Dec;48(1):1-0.
Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases: 2-Volume Set. Elsevier Health Sciences; 2014 Aug 28.
Baro M, Deubel TF. Persistent hunger: Perspectives on vulnerability, famine, and food security in sub-Saharan Africa. Annu. Rev. Anthropol.. 2006 Oct 21;35:521-38.
Musaiger AO, Hassan AS, Obeid O. The paradox of nutrition-related diseases in the Arab countries: the need for action. International journal of environmental research and public health. 2011 Sep;8(9):3637-71.
Atnafu A, Sisay MM, Demissie GD, Tessema ZT. Geographical disparities and determinants of childhood diarrheal illness in Ethiopia: further analysis of 2016 Ethiopian Demographic and Health Survey. Tropical Medicine and Health. 2020 Dec;48(1):1-2.
Baral R, Nonvignon J, Debellut F, Agyemang SA, Clark A, Pecenka C. Cost of illness for childhood diarrhea in low-and middle-income countries: a systematic review of evidence and modelled estimates. BMC public health. 2020 Dec;20:1-3.
Alene M, Yismaw L, Berelie Y, Kassie B. Health care utilization for common childhood illnesses in rural parts of Ethiopia: evidence from the 2016 Ethiopian demographic and health survey. BMC public health. 2019 Dec;19(1):1-2.
Richard SA, McCormick BJ, Seidman JC, Rasmussen Z, Kosek MN, Rogawski ET, Petri W, Bose A, Mduma E, Maciel BL, Chandyo RK. Relationships among common illness symptoms and the protective effect of breastfeeding in early childhood in MAL-ED: an eight-country cohort study. The American journal of tropical medicine and hygiene. 2018 Mar;98(3):904.
Alexander E, Hommeida S, Stephens MC, Manini ML, Absah I. The role of oral administration of immunoglobulin in managing diarrheal illness in immunocompromised children. Pediatric Drugs. 2020 Jun 1;22(3):331-4.
Fissehaye T, Damte A, Fantahun A, Gebrekirstos K. Health care seeking behaviour of mothers towards diarrheal disease of children less than 5 years in Mekelle city, North Ethiopia. BMC research notes. 2018 Dec;11(1):1-7.
Keto T, Alemu Y, Mamo A. Mothers’ perception and management preference of acute diarrheal disease. Int J Public Health. 2020 Dec;9(4):338-46.
Sarker AR, Sultana M, Mahumud RA, Ali N, Huda TM, Haider S, Rahman H, Islam Z, Khan JA, Van Der Meer R, Morton A. Economic costs of hospitalized diarrheal disease in Bangladesh: a societal perspective. Global health research and policy. 2018 Dec;3(1):1-2.
UNICEF. Multiple indicator survey. United Nations Children’s Fund 2000; 3.
V Kendall C. Public health and the domestic domain: lessons from anthropological research on diarrheal diseases. InAnthropology and primary health care 2019 Mar 7 (pp. 173-195). Routledge.
Mohmed EA, Abdalla MA. Awareness and Knowledge of Mothers Regarding Home Management of Diarrheal Disease for Children Less Than Five. International Journal of Healthcare and Medical Sciences. 2021;7(3):58-62.
Andualem Z, Dagne H, Taddese AA, Dagnew B. Mothers’ Handwashing Knowledge as a Predictor of Diarrheal Disease Among Under-Five Children Visiting Pediatric Ward in University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2019. Pediatric health, medicine and therapeutics. 2019;10:189.
Alghadeer S, Syed W, Alhossan A, Alrabiah Z, Babelghaith SD, Al Arifi MN, Alwhaibi A. Assessment of Saudi Mother’s Knowledge and Attitudes towards Childhood Diarrhea and Its Management. International Journal of Environmental Research and Public Health. 2021 Jan;18(8):3982.
Dev R, Williams-Nguyen J, Adhikari SP, Dev U, Deo S, Hillan E. Impact of maternal decision-making autonomy and self-reliance in accessing health care on childhood diarrhea and acute respiratory tract infections in Nepal. Public Health. 2021 Sep 1;198:89-95.
Tsehay CT, Aschalew AY, Dellie E, Gebremedhin T. Feeding Practices and Associated Factors During Diarrheal Disease Among Children Aged Less Than Five Years: Evidence from the Ethiopian Demographic and Health Survey 2016. Pediatric Health, Medicine and Therapeutics. 2021;12:69.
Rosyida DA, Hidayatunnikmah N. Maternal Attitude in the Handling of Diarrhea in Infant. Jurnal Medicoeticolegal Dan Manajemen Rumah Sakit. 2020 Apr 27;9(1):23-9.
King CK, Glass R, Bresee JS, Duggan C. Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy. MMWR Recomm Rep. 2003;52(RR-16):1-16.
WHO. Infant and young child feeding counseling: An integrated course. World Health Organization; 2006.
Shine S, Muhamud S, Adanew S, Demelash A, Abate M. Prevalence and associated factors of diarrhea among under-five children in Debre Berhan town, Ethiopia 2018: a cross sectional study. BMC infectious diseases. 2020 Dec;20(1):1-6.
Soboksa NE, Gari SR, Hailu AB, Alemu BM. Association between microbial water quality, sanitation and hygiene practices and childhood diarrhea in Kersa and Omo Nada districts of Jimma Zone, Ethiopia. PloS one. 2020 Feb 19;15(2):e0229303.
Belongia EA, Chyou PH, Greenlee RT, Perez-Perez G, Bibb WF, DeVries EO. Diarrhea incidence and farm-related risk factors for Escherichia coli O157: H7 and Campylobacter jejuni antibodies among rural children. The Journal of infectious diseases. 2003 May 1;187(9):1460-8.
Shemal AH. Epidemiology Of Diarrheal Diseases in Children Below 5 Years in Wassit Province. Al-Qadisiyah Medical Journal. 2014;10(17):141-7.
Abdul-hussein ZK, Raheema RH, Inssaf AI. Molecular diagnosis of diarrheagenic E. coli infections among the pediatric patients in Wasit Province, Iraq. Journal of Pure and Applied Microbiology. 2018 Dec 1;12(4):2229-41.
Hussein AA. Diarrhea among under-five Years children in Mosul City: Epidemiological and Microbiological study. Pak. J. Med. Health Sci. 2020;14(2):1060-3.
Tegen D, Damtie D, Hailegebriel T. Prevalence and Associated Risk Factors of Human Intestinal Protozoan Parasitic Infections in Ethiopia: A Systematic Review and Meta-Analysis. Journal of parasitology research. 2020 Oct 5;2020.
Mahal SS, Al-Omashi GB. Molecular Diagnosis and Genotype Analysis of Giardia lambelia in Diarrheal Patient in Al-Diwaniyah Province-Iraq. Indian Journal of Forensic Medicine & Toxicology. 2021 Apr 1;15(2).
Thiam S, Sy I, Schindler C, et al. Knowledge and practices of mothers and caregivers on diarrhoeal management among under 5-year-old children in a medium-size town of Senegal. Acta tropica 2019; 194: 155-64.
Ghasemi AA, Talebian A, Masoudi Alavi N, Moosavi GA. Knowledge of mothers in management of diarrhea in under-five children, in kashan, iran. Nurs midwifery stud. 2013;1(3):158-62.
Ehlayel MS, Bener A, Abdulrahman HM. Protective effect of breastfeeding on diarrhea among children in a rapidly growing newly developed society. Turk J Pediatr. 2009 Nov 1;51(6):527-33.
Alelign T, Asegidew W, Abera A. A cross sectional study on the incidence and risk factors of diarrheal illness among children under-five years of age in Debre Berhan town, Ethiopia. J Health Med Econ. 2016;2(2).
Alebel A, Tesema C, Temesgen B, Gebrie A, Petrucka P, Kibret GD. Prevalence and determinants of diarrhea among under-five children in Ethiopia: a systematic review and meta-analysis. PloS one. 2018 Jun 28;13(6):e0199684.
Megersa S, Benti T, Sahiledengle B. Prevalence of diarrhea and its associated factors among under-five children in open defecation free and non-open defecation free households in Goba District Southeast Ethiopia: a comparative cross-sectional study. Clinics Mother Child Health. 2019;16:324.
Getachew B, Mengistie B, Mesfin F, Argaw R. Factors associated with acute diarrhea among children aged 0-59 months in Harar town, eastern Ethiopia. East African Journal of Health and Biomedical Sciences. 2018 Nov 8;2(1):26-35.
Thabit MF, Hussian RR. Acute Infective Bloody Diarrhea in Children Below Five Years Admitted to Children Welfare Hospital in Medical City-Baghdad During 2015. Medico Legal Update. 2020 Apr 9;20(1):841-6.
Shrestha S, Aihara Y, Bhattarai AP, Bista N, Kondo N, Futaba K, Nishida K, Shindo J. Development of an objective water security index and assessment of its association with quality of life in urban areas of developing countries. SSM-population Health. 2018 Dec 1;6:276-85.
Komarulzaman A, Smits J, de Jong E. Clean water, sanitation and diarrhoea in Indonesia: Effects of household and community factors. Global public health. 2017 Sep 2;12(9):1141-55.
Otsuka Y, Agestika L, Widyarani NS, Yamauchi T. Risk factors for undernutrition and diarrhea prevalence in an urban slum in Indonesia: Focus on water, sanitation, and hygiene. The American journal of tropical medicine and hygiene. 2019 Mar;100(3):727.
Trudeau J, Aksan AM, Vásquez WF. Water system unreliability and diarrhea incidence among children in Guatemala. International journal of public health. 2018 Mar;63(2):241-50.
Alnawajha SK, Bakry GA, Aljeesh YI. Predictors of acute diarrhoea among hospitalized children in Gaza Governorates: a case-control study. Journal of health, population, and nutrition. 2015 Mar;33(1):1.
Boakye-Ansah AS, Ferrero G, Rusca M, Van Der Zaag P. Inequalities in microbial contamination of drinking water supplies in urban areas: the case of Lilongwe, Malawi. Journal of Water and Health. 2016 Oct;14(5):851-63.
Desta BK, Assimamaw NT, Ashenafi TD. Knowledge, practice, and associated factors of home-based management of diarrhea among caregivers of children attending under-five clinic in Fagita Lekoma District, Awi Zone, Amhara Regional State, Northwest Ethiopia, 2016. Nursing research and practice. 2017 Aug 21;2017.
Workie HM, Sharifabdilahi AS, Addis EM. Mothers’ knowledge, attitude and practice towards the prevention and home-based management of diarrheal disease among under-five children in Diredawa, Eastern Ethiopia, 2016: a cross-sectional study. BMC pediatrics. 2018 Dec;18(1):1-9.
Agegnehu MD, Bewket Zeleke L, Goshu YA, Ortibo YL, Mehretie Adinew Y. Diarrhea prevention practice and associated factors among caregivers of under-five children in Enemay District, Northwest Ethiopia. Journal of environmental and public health. 2019 May 12;2019.
Kebede Fufa W, Berhe Gebremedhin G, Gebregergs GB, Marama Mokonnon T. Assessment of poor home management practice of diarrhea and associated factors among caregivers of under-five years children in urban and rural residents of Doba Woreda, Ethiopia: Comparative cross-sectional study. International journal of pediatrics. 2019 Jun 2;2019.
Dodicho T. Knowledge and practice of mothers/caregivers on home management of diarrhea in under five children in Mareka district, Southern Ethiopia. Journal of Health, Medicine and Nursing. 2016;27(2422-8419):71-9.
Olakunle JM, Valentine UO, Kamaldeen AS, Buhari AS. Assessment of mothers' knowledge of home management of childhood diarrhea in a Nigerian setting. International Journal of Pharmaceutical Research and Bio-Science. 2012;1(4):168-84.
Doreen M. Othero. Home management of diarrhoea among underfives in a rural community, household preception and practice, 2008. Kenya: East African Journal of Public Health, East African Public Health Association; 2008: 142–146.
Manal M. Younus, Noor K. Ali, Hadeel R. Abdulqader; "Traditional Medicine in Iraq, is it still a source of serious adverse events?" A documentation of serious adverse events of Sagwa among infants in Iraqi Pediatric Hospitals, Iraqi New Medical Journal July 2017; 3 (2).
H.A.L. Catublas; "Knowledge, attitudes and practices in the use of herbal medicine: the case of urban and rural mothers in the Philippines"; Mahidol University Journal of Pharmaceutical Sciences, vol.43, pp.1-16 No.1, July-September 2016.
Shukur AM, Alezzi JI, Kadhim TJ. Morbidity and Mortality Associated with Community used Herbal (sagwa) use in Children with Acute Gastroenteritis in Diyala Governorate. Diyala Journal of Medicine. 2019 Dec 1;17(2):92-106.
Narjes Chyad Abdulzahra; "Attitude of Mothers toward Herbal Treatment of Their Children"; college of medicine, university of Kerbala. Karbala Journal Medicine. Vol.5, No.1, Dec, 2012
Justina Sunday Ikoedem, Chinweizu Ejikeme Udobi and Ememobong Gideon Asuquo "The Use of Medicinal Plants in the Treatment of Diarrhoea in Ibibio Land: A Survey" June 2018 with 53 Reads. Microbiology Research Journal 24(1):1-12.
Merga N, Alemayehu T. Knowledge, perception, and management skills of mothers with under-five children about diarrhoeal disease in indigenous and resettlement communities in Assosa District, Western Ethiopia. Journal of health, population, and nutrition. 2015 Mar;33(1):20.
Mukhtar A, Izham MI, Pathiyil RS. A survey of mothers' knowledge about childhood diarrhoea and its management among a marginalised community of Morang, Nepal. The Australasian medical journal. 2011;4(9):474.
Zahid SS, Zehra N, Ullah S, Khan N, Javed MH, Khan M. Mother's awareness and practices regarding home management of childhood diarrhea in a squatter settlement in Karachi. Pak J Med Dent. 2014;3(2):1-5.
Raji MO, Abdullahi U, Raji IA, Oladigbolu RA, Kaoje AU, Awosan KJ. Caregivers knowledge, home treatment of diarrhoea disease and predictors of child diarrhoea disease in a semi urban community of Sokoto, North-west, Nigeria. Journal of Public Health and Epidemiology. 2017 Feb 28;9(2):16-23.
Mwambete KD, Joseph R. Knowledge and perception of mothers and caregivers on childhood diarrhoea and its management in Temeke municipality, Tanzania. Tanzania journal of health research. 2010;12(1):47-54.
Shah D, Choudhury P, Gupta P, Mathew JL, Gera T, Gogia S, et al. Promoting appropriate management of diarrhea: a systematic review of literature for advocacy and action: UNICEFPHFI series on newborn and child health, India. Indian Pediatr. 2012;49(8):627-49.
Mengistie B, Berhane Y, Worku A. Predictors of Oral Rehydration Therapy use among under-five children with diarrhea in Eastern Ethiopia: a community based case control study. BMC Public Health. 2012;12(1):1029.
Gazi E, Chowdhury A, Kumar R, Sarkar AP, Basu SS, Saha S. Can mothers care for acute diarrhoeal disease of their under five children effectively at home? a cross sectional study in slum community in bankura. Journal of Evidence Based Medicine and Healthcare. 2015;2(36):5575-84.
Ogunrinde OG, Raji T, Owolabi OA, Anigo KM. Knowledge, attitude and practice of home management of childhood diarrhoea among caregivers of under-5 children with diarrhoeal disease in Northwestern Nigeria. Journal of tropical pediatrics. 2012 Apr 1;58(2):143-6.
Abdinia B. Knowledge and practice of mothers in the management of children’s Diarrhea, in Northwest, Iran. Arch Pediatr. 2014 Oct;2(4):e17581.
Ghasemi AA, Talebian A, Masoudi Alavi N, Moosavi GA. Knowledge of mothers in management of diarrhea in under-five children, in kashan, iran. Nurs midwifery stud. 2013;1(3):158-62.
Okoh BA, Alex–Hart BA. Home management of diarrhoea by caregivers presenting at the diarrhoea training unit of a tertiary hospital in Southern Nigeria. Journal of Advances in Medicine and Medical Research. 2014 Aug 3:5524-40.
Hasan MM, Richardson A. How sustainable household environment and knowledge of healthy practices relate to childhood morbidity in South Asia: analysis of survey data from Bangladesh, Nepal and Pakistan. BMJ open. 2017 Jun 1;7(6):e015019.
Anidi I, Bazargan M, James FW. Knowledge and management of diarrhoea among undeserved minority parents/caregivers. Ambul Pediatr. 2002;2(3):201–6.
Jha N, Singh R, Baral D. Knowledge, attitude and practices of mothers regarding home management of acute diarrhoea in Sunsari, Nepal. Nepal Med Coll J. 2006;8(1):27–30.
Datta V, John R, Singh VP, Chaturvedi P. Maternal knowledge, attitude and practices towards diarrhoea and oral rehydration therapy in rural Maharashtra. Indian J Pediatr. 2001;68(11):1035–7.
Rasania SK, Singh D, Pathi S, Matta S, Singh S. Knowledge and attitude of mothers about oral rehydration solution in few urban slums of Delhi. Health Popul Perspect Issues. 2005;28(2):100–7.
MacDonald SE, Moralejo DG, Mathews MK. Maternal understanding of diarrhoea-related dehydration and its influence on ORS use in Indonesia. Asia Pac J Public Health. 2007;19(1):34–9. [PubMed] [Google Scholar]
Gupta N, Jain SK, Ratnesh, Chawla U, Hossain S, Venkatesh S. An evaluation of diarrheal diseases and acute respiratory infections control programmes in a Delhi slum. Indian J Pediatr. 2007;74(5):471–6. [PubMed]
Delgado MF, Sierra CH, Calvache JA, Rios AM, Mosquera C, Salas I, Agredo F, Meneses R. Maternal knowledge about children's danger signs in acute diarrhoea in an IMCI's frame. Colomb Med. 2006;37(4):293–8.