Though severe side effects were not found in Ali’s investigation [1] and were not reported previously in adolescents following vaccinations with the mRNA-1273 SARS-CoV-2 vaccine(Moderna), there are several reports of severe adverse reactions to this vaccine in adults. 

 In a 22yo male with a history of mild COVID-19 6m prior, peri-myocarditis developed 3d after the first dose of the Moderna vaccine [2]. The patient markedly benefited from aspirin and colchicine [2].

A 77yo male developed immune encephalitis, myoclonus, and Sweet-syndrome 1d after the first Moderna dose [3]. He profited significantly from methyl-prednisolone.[3]

A 60yo male with a history of hepatitis-C, renal insufficiency, hypertension, and heart failure, presented with purpuric rash and thrombocytopenia (84000/µL) without major bleeding 2d after the first Moderna dose [4]. 

A 66yo male developed a large-area, painful blistering rash 1d after the second Moderna dose [5]. He benefited from mupirocin and prednisone.

One day after the second Moderna dose, a 34yo male developed myocarditis. Aspirin, colchicine, bisoprolol and rampiril were beneficial.

Though severe adverse reactions to Moderna are rarely reported, they might be harmful to those experiencing them.